HYDRAZINE METER SOLUTION
CAS: 100-10-7
Molecular Formula: C9H11NO
HYDRAZINE METER SOLUTION - Names and Identifiers
| Synonyms | ERLICH'S REAGENT EHRLICH'S REAGENT EHRLICH'S REAGENT SICC HYDRAZINE METER SOLUTION DIMETHYLAMINOBENZALDEHYDE P-dimethylaminobenzaldehyde test solution(ChP) 4-(Dimethylamino)benzaldehyde test solution(ChP) |
| CAS | 100-10-7 |
| EINECS | 202-819-0 |
| InChIKey | BGNGWHSBYQYVRX-UHFFFAOYSA-N |
HYDRAZINE METER SOLUTION - Physico-chemical Properties
| Molecular Formula | C9H11NO |
| Molar Mass | 149.19 |
| Density | 1.10g/mLat 20°C |
| Melting Point | 72-75°C(lit.) |
| Boling Point | 176-177 °C (17 mmHg) |
| Flash Point | 164 °C |
| Water Solubility | 0.3 g/L (20 ºC) |
| Solubility | alcohol: passes test (APHA ≤60) |
| Appearance | Liquid |
| Color | White to pale yellow |
| Odor | Characteristic odor |
| Merck | 14,3230 |
| BRN | 606802 |
| pKa | pK1:1.647(+1) (25°C) |
| Storage Condition | 2-8°C |
| Stability | Stable, but light sensitive. Incompatible with bases, strong oxidizing agents. |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.417 |
| Physical and Chemical Properties | White or yellowish foliate crystals or powders. Melting point 74 ℃, boiling point 176-177 ℃(2.27kPa), flash point 164 ℃. Soluble in alcohol, ether, acetone, chloroform and acetic acid, slightly soluble in water. It has a benzaldehyde-like smell and gradually changes to red when exposed to light. |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| Caution | Positive is red (contact surface), that is, rose indole is formed, which belongs to a color reaction reagent, the main component is p-dimethylaminobenzaldehyde, etc. |
HYDRAZINE METER SOLUTION - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R22 - Harmful if swallowed R67 - Vapors may cause drowsiness and dizziness R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R10 - Flammable R66 - Repeated exposure may cause skin dryness or cracking R37 - Irritating to the respiratory system R34 - Causes burns R20 - Harmful by inhalation R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36 - Irritating to the eyes R11 - Highly Flammable |
| Safety Description | S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. |
| UN IDs | UN 2920 8/PG 2 |
| WGK Germany | 1 |
| RTECS | CU5775000 |
| FLUKA BRAND F CODES | 8 |
| TSCA | Yes |
| HS Code | 29223900 |
| Toxicity | LD50 orally in Rabbit: > 6400 mg/kg |
HYDRAZINE METER SOLUTION - Introduction
Also known as Euclidean liquid/E reagent or indole reagent or indigo matrix reagent, it is mainly used for the identification of Enterobacteriaceae, non-fermentative bacteria, and anaerobic bacteria, and the detection of indole derivatives and amines. Positive is red (contact surface), that is, rose indole is formed, which belongs to a color reaction reagent, the main component is p-dimethylaminobenzaldehyde, etc.
Last Update：2022-10-16 17:33:54
HYDRAZINE METER SOLUTION - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | p-dimethylaminobenzaldehyde is an organic intermediate, which can be prepared from N,N-dimethylaniline and DMF. It is reported that p-dimethylaminobenzaldehyde can be used to prepare high purity DAST source powder, and can also be used to prepare color solution to analyze aminohydroxyurea. |
| Application | 1. Dye intermediates and Analytical reagents. The product for the determination of indole, skatole, urinary Cyanogen, tryptophan and ergotoxine, but also to distinguish between serum rash and scarlet fever. 2. In terms of dyes, it can be used to synthesize pressure-sensitive dyes. It is also used for the production of cationic brilliant red G(C.I. Basicred 52). It can also be used as dye intermediates; As reagents for the determination of urobilin, indole, alkaloids, etc. and chromatographic analysis reagents. 3. Determination of indole, skatole, urinary Cyanogen, tryptophan, albumin, hydrogen peroxide, arsfan sodium, anthranilic acid, antipyrine, etc., also used to distinguish the serum rash and red fever. 4. Manufacture of dye. 5. Reagents for the detection of amino acids, peptides, amines, indole, hydrazine, hydrogen peroxide, anthranilic acid, antipyrine and ergotoxine; Reagents for the development of tryptophan; For the detection of tryptophan in proteins; test reagents for the identification of indole-producing microorganisms; Can react with pyrrole and primary amines to produce colored condensation products (Schiff bases). |
| preparation | add 4.9g(0.032mol) of phosphorus oxychloride in a three-necked bottle, slowly drop 2.5g(0.031mol)DMF under ice bath, drop (8min), stir for 10min, slowly drop add 3.66g(0.03mol) N to the three-necked bottle, N-dimethylaniline (10min), after dropping, the reaction solution was transferred to boiling water bath for 2H. After reaction, the reaction solution was poured into 20ml of ice water, and adjusted to PH = 4 with 30% sodium hydroxide solution, the crystals were left to stand and crystallize, then filtered with suction the next day to obtain a pale yellow or nearly colorless solid, which was recrystallized with 30ml of ethanol-water (1:2.5V/V) to obtain p-dimethylaminobenzaldehyde. |
| Use | dye intermediates and Analytical reagents. The product for the determination of indole, skatole, urinary Cyanogen, tryptophan and ergotoxine, but also to distinguish between serum rash and scarlet fever. In terms of dyes, it can be used to synthesize pressure-sensitive dyes. It was also used to produce cationic brilliant Red G(C.I.Basic Red 52). used as dye intermediates used as reagents for the determination of urobilin, indole, alkaloids and other chromatographic analysis reagents determination of indole, skatole, urinary Cyanogen, tryptophan, albumin, hydrogen peroxide, arsfan sodium, anthranilic acid, antipyrine, etc., also used to distinguish between serum rash and red fever. Manufacture of dyes. reagents for the detection of amino acids, peptides, amines, indole, hydrazine, hydrogen peroxide, anthranilic acid, antipyrine and ergotoxine; Reagents for the development of tryptophan; For the detection of tryptophan in proteins; test reagent for identification of indole-producing microorganisms; Can react with pyrrole and primary amine to produce colored condensation products (Schiff base) also known as Euclidean liquid/E reagent, mainly used for Enterobacter, identification of non-fermenting bacteria, fastidious bacteria and anaerobic bacteria, detection of indole derivatives and amines |
| production method | with N,N-dimethylaniline as raw material, can be produced by two methods. (1) Methylene-N,N-dimethylaminobenzylamine is produced by the reaction of urotropine, and N,N-dimethylbenzylidene methylamine is produced by translocation, and then the product is hydrolyzed. (2) reaction with dimethylformamide in the presence of phosphorus oxychloride. In addition, there is a laboratory preparation method, N,N-dimethylaniline, sodium nitrite, formaldehyde as raw material preparation. |
| autoignition temperature | 445°C |
Last Update：2024-04-09 02:00:13
